Neuroscience Research group · Acıbadem Mehmet Ali Aydınlar University
Süyen Lab
Epilepsy and autism, studied with behavioural research and NMR-based biomarker discovery.
- 5members
- 4projects
- 2partners
What we work on
Süyen Lab was founded by Prof. Güldal Süyen and brings together researchers from medicine, engineering, veterinary medicine and biology. The team focuses on neurological diseases, with particular emphasis on epilepsy and autism. In epilepsy the laboratory aims to contribute to biomarker discovery and to the development of new treatment approaches; to this end it combines behavioural studies with technologies such as nuclear magnetic resonance (NMR) spectroscopy.
Ongoing projects include metabolomic profiling of epileptogenesis in a lithium–pilocarpine temporal lobe epilepsy rat model (ABAPKO, 2023–2024); the effects of cytidine 5′-diphosphocholine and uridine monophosphate in a valproic acid rat model of autism (ABAPKO, 2024–2025); neuronal activity and behavioural change in a pentylenetetrazole seizure model in zebrafish, with the Kavli Institute for Systems Neuroscience in Norway; and the DLK inhibitor GNE-3511 in a pilocarpine temporal lobe epilepsy mouse model, with UC San Diego. The last two run under the TÜBİTAK 2214-A International Research Fellowship Programme.
Alongside its research the laboratory mentors medical students and supports young researchers interested in neurophysiology.
Team 5
Principal investigator
Prof. Güldal Süyen
Professor of Physiology; founder of Süyen Lab
Founded Süyen Lab, which studies epilepsy and autism through behavioural research and NMR-based biomarker discovery.
- Samed Özer PhD Student
- Merve Antmen PhD Student
- Sümeyye Çilingir PhD Student
- Dilan Acar Postgraduate Research Student
Projects & funders
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Metabolomic biomarkers of epileptogenesis by NMR spectroscopy in a lithium–pilocarpine temporal lobe epilepsy model
Identification of potential biomarkers of epileptogenesis through metabolomic profiling using nuclear magnetic resonance (NMR) spectroscopy in a lithium–pilocarpine-induced temporal lobe epilepsy rat model.
- Funder
- ABAPKO — ACU Scientific Research Projects Commission · ABAPKO internal research project
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CDP-choline and uridine monophosphate in a valproic acid rat model of autism
Investigation of the effects of cytidine 5′-diphosphocholine and uridine monophosphate in a valproic acid-induced rat model of autism.
- Funder
- ABAPKO — ACU Scientific Research Projects Commission · ABAPKO internal research project
-
Neuronal activity and behaviour in a pentylenetetrazole seizure model in juvenile zebrafish
Evaluation of neuronal activity and cognitive/behavioural changes during the juvenile stage in a pentylenetetrazole-induced seizure model in zebrafish, in collaboration with the Kavli Institute for Systems Neuroscience.
- Funder
- TÜBİTAK — Scientific and Technological Research Council of Türkiye · TÜBİTAK 2214-A International Research Fellowship Programme
- Partners
- Kavli Institute for Systems Neuroscience, NTNU (Norway)
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The DLK inhibitor GNE-3511 in a pilocarpine temporal lobe epilepsy mouse model
Effects of the dual leucine zipper kinase inhibitor GNE-3511 on epileptogenesis and cognitive–behavioural changes, in collaboration with the University of California, San Diego.
- Funder
- TÜBİTAK — Scientific and Technological Research Council of Türkiye · TÜBİTAK 2214-A International Research Fellowship Programme
- Partners
- University of California, San Diego (United States)
Collaborations 2
- Kavli Institute for Systems Neuroscience, NTNU Trondheim, Norway
- University of California, San Diego San Diego, United States
From the group
Can a brain recording warn you before a seizure?
Assoc. Prof. Kerem Aksoy and an international collaborator discuss long-term brain recordings, false alarms and what a useful seizure warning would look like.
Visit by Our University Delegation to Karolinska Institutet for Scientific Collaboration
Prof. Güldal Süyen, Vice Rector of Acıbadem University, and Prof. Yasemin Alanay, Director of ACURARE, visited Karolinska Institutet in Sweden.
TÜSEB-Acıbadem University Cooperation Agreement
A cooperation protocol has been signed between Acıbadem University and the Turkish Health Institutes Presidency (TÜSEB).
Join us
Medical students, doctoral candidates and visiting researchers with an interest in neurophysiology are welcome to get in touch.
Open to rotation students
Write to the group