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Portrait of Prof. Güldal Süyen

Prof. Güldal Süyen

Professor of Physiology; founder of Süyen Lab

Department of Physiology · School of Medicine Acıbadem Mehmet Ali Aydınlar University

About

Founded Süyen Lab, which studies epilepsy and autism through behavioural research and NMR-based biomarker discovery.

  • epilepsy
  • autism
  • neurophysiology
  • NMR metabolomics
  • animal models

Prof. Güldal Süyen founded Süyen Lab, which brings together researchers from medicine, engineering, veterinary medicine and biology. The group focuses on neurological diseases, with particular emphasis on epilepsy and autism, and aims to contribute to biomarker discovery and new treatment approaches.

Current projects include NMR-based metabolomic profiling of epileptogenesis in a lithium–pilocarpine rat model (ABAPKO, 2023–2024), the effects of CDP-choline and uridine monophosphate in a valproic acid model of autism (ABAPKO, 2024–2025), and two TÜBİTAK 2214-A collaborations with the Kavli Institute for Systems Neuroscience in Norway and UC San Diego. She is Vice Chair of the university's Animal Experiments Local Ethics Committee (ACU-HADYEK) and leads the Behaviour, Epilepsy and Autism student research team.

Research output

  • 82publications
  • 17projects
  • 14theses supervised

Figures as recorded in AVESİS, the university’s research information system · AVESİS profile.

Projects & funding

  • 2021–2024 Principal investigator

    Production of an anti-CX3CR1 monoclonal antibody for the preclinical treatment of pancreatic cancer and chronic pancreatitis

    Project team: CEYHAN G. O. (Executive), KOCAGÖZ Z. T., Demir E., Hatipoğlu İ., SEVER E., SÜYEN G..

    Funder
    TÜBİTAK — Scientific and Technological Research Council of Türkiye · TUBITAK Project, 1001 - Program for Supporting Scientific and Technological Research Projects
  • 2023–2024 Principal investigator

    Metabolomic biomarkers of epileptogenesis by NMR spectroscopy in a lithium–pilocarpine temporal lobe epilepsy model

    Identification of potential biomarkers of epileptogenesis through metabolomic profiling using nuclear magnetic resonance (NMR) spectroscopy in a lithium–pilocarpine-induced temporal lobe epilepsy rat model.

    Funder
    ABAPKO — ACU Scientific Research Projects Commission · ABAPKO internal research project
  • 2024–2025 Principal investigator

    CDP-choline and uridine monophosphate in a valproic acid rat model of autism

    Investigation of the effects of cytidine 5′-diphosphocholine and uridine monophosphate in a valproic acid-induced rat model of autism.

    Funder
    ABAPKO — ACU Scientific Research Projects Commission · ABAPKO internal research project
  • Partner

    Neuronal activity and behaviour in a pentylenetetrazole seizure model in juvenile zebrafish

    Evaluation of neuronal activity and cognitive/behavioural changes during the juvenile stage in a pentylenetetrazole-induced seizure model in zebrafish, in collaboration with the Kavli Institute for Systems Neuroscience.

    Funder
    TÜBİTAK — Scientific and Technological Research Council of Türkiye · TÜBİTAK 2214-A International Research Fellowship Programme
    Partners
    Kavli Institute for Systems Neuroscience, NTNU (Norway)
  • Partner

    The DLK inhibitor GNE-3511 in a pilocarpine temporal lobe epilepsy mouse model

    Effects of the dual leucine zipper kinase inhibitor GNE-3511 on epileptogenesis and cognitive–behavioural changes, in collaboration with the University of California, San Diego.

    Funder
    TÜBİTAK — Scientific and Technological Research Council of Türkiye · TÜBİTAK 2214-A International Research Fellowship Programme
    Partners
    University of California, San Diego (United States)

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