Prof. Güralp Onur Ceyhan
Professor of General Surgery; lead of the Pancreatic Cancer Research Center (PANKAM)
Department of General Surgery · School of Medicine Acıbadem Mehmet Ali Aydınlar University
About
Leads PANKAM, where surgeons and scientists study how nerves and pancreatic cancer cells interact and turn that knowledge into treatments.
- pancreatic cancer
- cancer neuroscience
- neural invasion
- organoids
- pancreatic surgery
Prof. Güralp Onur Ceyhan is a general surgeon and the lead of the Pancreatic Cancer Research Center (PANKAM) at Acıbadem University. The centre's team studies the interaction between nerves and cancer cells in pancreatic cancer, from the neural niche in which tumour cells survive neoadjuvant therapy to the sensory neurons that drive progression through neuron–cancer pseudo-synapses.
His recent work with the PANKAM team and partners in Munich appears in Cancer Cell, Cancer Letters, Science Signaling and Langenbeck's Archives of Surgery. He also supervises the School of Medicine's Pancreatic Diseases student research group.
Research output
- 245publications
- 10,654citations
- 60h-index
- 15projects
Figures as recorded in AVESİS, the university’s research information system · AVESİS profile.
Projects & funding
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Drug repurposing and losartan-mediated NF-κB pathway blockade in the neural invasion of pancreatic cancer
Project team: KARAKAŞ ZEYBEK D. (Executive), CEYHAN G. O., DUMAN E., Kasapoğlu T..
- Funder
- ABAPKO — ACU Scientific Research Projects Commission · Project Supported by Higher Education Institutions, BAP Other
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Modulation of NK cell function by acetylsalicylic acid through the pancreatic cancer cell secretome
Project team: KARAKAŞ ZEYBEK D. (Executive), CEYHAN G. O., Kasapoğlu T..
- Funder
- ABAPKO — ACU Scientific Research Projects Commission · Project Supported by Higher Education Institutions, BAP Research Project
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Characterisation of nerve-associated cancer-associated fibroblast subtypes in pancreatic cancer and their contribution to neural invasion
Project team: KARAKAŞ ZEYBEK D. (Executive), Sığırlı S., CEYHAN G. O..
- Funder
- ABAPKO — ACU Scientific Research Projects Commission · Project Supported by Higher Education Institutions, BAP PhD
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Genomic analysis and targeting of neural invasion in pancreatic cancer
Project team: CEYHAN G. O. (Executive), KARAKAŞ ZEYBEK D., Kavaklıoğlu B..
- Funder
- ABAPKO — ACU Scientific Research Projects Commission · Project Supported by Higher Education Institutions, BAP PhD
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Effect of NMDAR1A receptor inhibition on neuropathic pain in chronic pancreatitis
Project team: Ceyhan G. O. (Executive).
- Funder
- TÜBİTAK — Scientific and Technological Research Council of Türkiye · TUBITAK Project, 1001 - Program for Supporting Scientific and Technological Research Projects
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Emergency R&D Project of Group A
Project team: Karakaş Zeybek D. (Executive), Ceyhan G. O..
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Production of an anti-NPY monoclonal antibody for the preclinical treatment of pancreatic cancer
Project team: Ceyhan G. O. (Executive), CAN Ö..
- Funder
- TÜSEB — Turkish Institutes of Health · Research Project of the Presidency of Turkey Health Institutes (TÜSEB)
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Production of an anti-CX3CR1 monoclonal antibody for the preclinical treatment of pancreatic cancer and chronic pancreatitis
Project team: CEYHAN G. O. (Executive), KOCAGÖZ Z. T., Demir E., Hatipoğlu İ., SEVER E., SÜYEN G..
- Funder
- TÜBİTAK — Scientific and Technological Research Council of Türkiye · TUBITAK Project, 1001 - Program for Supporting Scientific and Technological Research Projects
Show all 14 projects
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Deciphering and Targeting Neural Invasion in Pancreatic Cancer
Project team: Sever E., Sezerman O. U., Kocagöz Z. T., Demir E., İnce Ü., Ceyhan G. O. (Executive).
- Funder
- TÜBİTAK — Scientific and Technological Research Council of Türkiye · TUBITAK Project, 2223 - Domestic Scientific Activities Support Program
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The effect of mast cell stabilizers on pain emergence and perception in the chronic panceatitis
Project team: Ceyhan G. (Executive).
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The mechanistic characterization of Neuro-Cancer-Stellate-Cell interactions in pancreatic cancer
Project team: Ceyhan G. (Executive).
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The impact of fractalkine/ CX3CR1 on the course and pain generation in experimental pancreatitis
Project team: Ceyhan G. O. (Executive).
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Neuronal plasticity in pancreatic neuropathy and neuropathic pancreatic pain: a prospective clinical, neuroradiological, histopathological and molecular biological investigation
Project team: Ceyhan G. O. (Executive).
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Perineural invasion in pancreatic carcinoma.
Project team: Ceyhan G. O. (Executive).
In the news
ALIS26 Oncoverse Brought Together Pioneers of Cancer Research at Acıbadem University
ALIS26 Oncoverse Brought Together Pioneers of Cancer Research at Acıbadem University
Prof. Güralp Onur Ceyhan Appointed as a Working Group Member in a COST Action
Prof. Güralp Onur Ceyhan Appointed as a Working Group Member in a COST Action
Prof. Dr. Güralp Onur Ceyhan, Elected as a Council Member of the World Pancreas Organization
Prof. Güralp Onur Ceyhan, from Department of General Surgery, School of Medicine, has been elected as a Council Member of the International Association of Pancreatology (IAP). We congratulate our distinguished faculty member and wish him continued success.
