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Rare diseases & genomics Research group · Acıbadem Mehmet Ali Aydınlar University

IMGAL — Molecular Genetics Laboratory

Finding the genetic defects behind neurological and autoinflammatory diseases, from familial sequencing to cell models.

  • 1member
  • 1project
  • 4partners
Researcher reading results on a screen beside an analyser

What we work on

IMGAL conducts research in human molecular genetics with the aim of identifying the genetic defects underlying disease. The research led by Prof. Eda Tahir Turanlı focuses on the genetics and epigenetics of neurological and autoinflammatory diseases: the team identifies candidate genes in familial cases through genomic sequencing, genotyping and bioinformatics analyses, then characterises the genetic variants functionally in cell culture models. Its primary areas are multiple sclerosis and rare autoinflammatory diseases.

The laboratory's activities began in 2001 at Boğaziçi University and continued from 2005 in the Department of Molecular Biology and Genetics at İstanbul Technical University before moving to Acıbadem University, where Prof. Tahir Turanlı has headed the department since 2021. IMGAL collaborates with İstanbul University-Cerrahpaşa, Marmara University, the US National Institutes of Health (NIAID and NINDS) and Virginia Commonwealth University.

Lab website

Team 1

Principal investigator Prof. Eda Tahir Turanlı Professor and Head of Molecular Biology and Genetics; lead of IMGAL Studies the genetics and epigenetics of neurological and autoinflammatory diseases, with multiple sclerosis and rare autoinflammatory disorders as the main lines.

Projects & funders

  • Since 2019 Principal investigator

    Multiple sclerosis genome research

    With Dr. Michael Lenardo (NIAID) and Dr. Daniel Reich (NINDS), National Institutes of Health. Ongoing.

    Partners
    National Institutes of Health (NIAID, NINDS) (United States)

Collaborations 4

National Institutes of Health (NIAID, NINDS), Bethesda Virginia Commonwealth University, Richmond İstanbul University-Cerrahpaşa, İstanbul Marmara University, İstanbul Acıbadem University, İstanbul
  • National Institutes of Health (NIAID, NINDS) Bethesda, United States
  • Virginia Commonwealth University Richmond, United States
  • İstanbul University-Cerrahpaşa İstanbul, Türkiye
  • Marmara University İstanbul, Türkiye

From the group

Join us

Graduate students in molecular biology and genetics and clinicians with familial cases are welcome to get in touch.

Open to rotation students

Write to the group