Test & analysis catalogue (ACUTAB)
The ACU Test and Analysis Unit (ACUTAB) carries out research and analysis to national and international standards for researchers at the university and in industry. The list below reproduces the published test list by laboratory; application forms for each service are on the ACUTAB pages of the university site, and prices are set after the application is reviewed.
Overview
How to apply: complete and sign the request form for the test and send it to acutab@acibadem.edu.tr. Once the request is evaluated and approved, the full fee is deposited to the specified bank account and the receipt is forwarded; samples are delivered in the quantity and packaging specified, with a label carrying the information requested in the report. Fees exclude 20% VAT and may change without notice, but no increase applies during a project period once the fee is transferred. A single report is issued per application unless separate reports are requested; a second-language report carries an additional fee; returned samples are shipped receiver-pays.
Cell Culture Laboratory
| No | Service |
|---|---|
| 1 | Cell expansion and maintenance (25 cm² flask) |
| 2 | Cell expansion and maintenance (75 cm² flask) |
| 3 | Cell freezing (3×10⁶ cells/ml) |
| 4 | Mycoplasma testing of cell-culture samples by PCR |
| 5 | Mycoplasma testing of cell-culture samples with the MycoTOOL PCR detection kit |
Molecular Biology Laboratory
| No | Service |
|---|---|
| DNA ISOLATION | |
| 1 | Isolation from mammalian cells |
| 2 | Genomic DNA isolation from microorganisms |
| 3 | Plasmid DNA isolation from microorganisms |
| 4 | DNA isolation from agarose gel |
| DNA QUANTIFICATION | |
| 1 | Imaging by agarose gel electrophoresis |
| 2 | DNA quantity and purity measurement |
| CLONING AND GENETIC MODIFICATION | |
| 1 | PCR amplification |
| 2 | Site-directed mutagenesis (SDM), deletion, insertion |
| 3 | Gene synthesis / cloning 1 |
| 4 | Gene synthesis / cloning 2 |
| RNA WORK | |
| 1 | RNA quantity and purity measurement |
| 2 | RNA isolation from mammalian cells |
| GENE EXPRESSION ANALYSIS | |
| 1 | RNA isolation from tissue or cells |
| 2 | RNA isolation from tissue or cells |
| 3 | RNA isolation from tissue or cells |
| 4 | cDNA synthesis |
| 5 | cDNA synthesis |
| 6 | cDNA synthesis |
| Flow cytometry analyses | |
| 1 | Measurement of mitochondrial function |
| 2 | CD surface antigen staining |
| INFLAMMASOME STIMULATION | |
| 1 | Cell freezing (10×10⁶ cells/ml) |
| 2 | Functional analyses and immunological studies |
| INTERFERON GENE EXPRESSION ANALYSIS | |
| 1 | RNA isolation from tissue or cells (1–5 samples) |
| 2 | RNA isolation from tissue or cells (6–20 samples) |
| 3 | RNA isolation from tissue or cells (>20 samples) |
| 4 | cDNA synthesis (1–5 samples) |
| 5 | cDNA synthesis (6–20 samples) |
| 6 | cDNA synthesis (>20 samples) |
| 7 | Real-time PCR (qPCR) (1–5 samples) |
| 8 | Real-time PCR (qPCR) (6–20 samples) |
| 9 | Real-time PCR (qPCR) (>20 samples) |
Microbiology Laboratory
| No | Service |
|---|---|
| 1 | AMES mutagenicity test |
| 2 | AMES mutagenicity test kit production |
| 3 | Minimum bactericidal concentration |
| 4 | Minimum inhibitory concentration |
| 5 | Disinfectant efficacy test |
| 6 | Air-cleaning device efficacy test |
| 7 | Efficacy test of UV sterilisation devices |
| 8 | Genomic DNA isolation from microorganisms |
| 9 | Plasmid DNA isolation from microorganisms |
| 10 | Antibacterial activity on non-porous surfaces (ISO 22196) |
Electrophoresis and Western Blot Laboratory
| No | Service |
|---|---|
| PROTEIN ELECTROPHORESIS | |
| SDS-polyacrylamide (Laemmli type) | |
| 1 | 9 samples + marker (Coomassie blue) |
| 2 | 9 samples + marker (silver staining) |
| MEMBRANE TRANSFER OF PROTEINS AND ENZYMATIC DETECTION | |
| 1 | Semi-dry electrophoretic transfer (PVDF, nitrocellulose, nylon membrane), 9 samples + marker |
| 2 | Wet transfer, 9 samples + marker |
In Vitro Biocompatibility Laboratory
| No | Service |
|---|---|
| 1 | Cytotoxicity test (ISO 10993-5, biocompatibility testing of medical devices, cosmetics and drugs) |
| 2 | Ocular irritation test – EpiOcular™ (OECD TG 492) |
| 3 | Skin irritation test – in vitro EpiDerm™ (OECD TG 439) |
| 4 | Skin corrosion test – in vitro EpiDerm™ (OECD TG 431) |
| 5 | Haemocompatibility test (ISO 10993-4) |
Bioproduction Laboratory
| No | Service |
|---|---|
| 1 | Cloning (Escherichia coli, Pichia pastoris and others) |
| 2 | Recombinant protein production in yeast |
| 3 | Protein purification (Ni-NTA / ion-exchange chromatography) |
| 4 | Cellulase activity assays (colorimetric, fluorometric) |
| 5 | Cutinase / esterase activity assays (colorimetric, fluorometric) |
| 6 | Directed mutagenesis |
| 7 | Rational protein design |
| 8 | Bradford protein assay |
| 9 | BCA protein assay |
| 10 | Cytotoxicity tests (HepG2 cell line, WST-8) |
| 11 | Antimicrobial activity assay (E. coli, S. aureus, P. aeruginosa, C. albicans and others) |
| 12 | Enzymatic biodegradation tests |
Microscopy Laboratory
| No | Service |
|---|---|
| 1 | Tissue processing and paraffin embedding |
| 2 | Decalcification |
| 3 | Microtome sectioning |
| 4 | Frozen sectioning (fresh, unfixed tissue only) |
| 5 | Haematoxylin–eosin and other special stains |
| 6 | Immunohistochemistry |
| 7 | Histomorphometric analysis and reporting |
| 8 | Histological and histopathological analysis and reporting |
| Confocal microscopy analyses | |
| 1 | 2D imaging |
| 2 | 3D imaging (z-stacking) |
Nanobiotechnology Laboratory
| No | Service |
|---|---|
| 1 | Solid-phase peptide synthesis |
| 2 | Dielectric constant of solid dielectric materials (ASTM D150) |
| 3 | Discussion and consultancy on projects involving computational protein and peptide structure analysis |
| 4 | Literature and database search for projects involving computational protein and peptide structure analysis |
| 6 | Zetasizer nano-scale particle sizing |
| 7 | Zetasizer zeta potential measurement |
Chromatography and Spectroscopy Laboratory
| No | Service |
|---|---|
| UV-Vis spectrometry analyses | |
| 1 | UV-Vis absorbance measurement (at a given wavelength) |
| 2 | UV-Vis spectrum acquisition (over a wavelength range) |
| 3 | Quantitative analysis – standard curve |
| 4 | Quantitative analysis – sample analysis |
| 5 | Kinetic analysis |
| 6 | Interpretation of results and reporting |
| Nuclear magnetic resonance (NMR) spectroscopy analyses | |
| 1 | 1H |
| 2 | 13C (1 hour) |
| 3 | IVDr analysis (serum, plasma, urine, cerebrospinal fluid) |
| 4 | 2D-COSY, HMBC, HSQC, TOCSY (1 hour) |
| 5 | APT, DEPT |
| LC-MS analyses | |
| 1 | Sample dissolution / preparation |
| 2 | C18-column purity determination |
| 3 | C18-column mass analysis |
| 4 | Azo dye analysis |
| * Prices are for a single-run analysis and include the mobile phase. | |
| LC-MS/MS analyses | |
| 1 | Sample dissolution / preparation |
| 2 | Qualitative analysis |
| Range scan by MS2 scan | |
| Target-ion search by MS2 SIM | |
| 3 | Quantitative analysis |
| MRM method development | |
| Preparation of standard samples | |
| Calibration curve preparation | |
| Quantitative analysis calculations | |
| * Prices are for a single-run analysis and include the mobile phase. | |
| Gas chromatography analyses | |
| 1 | GC-MS analysis* |
| 2 | GC-FID analysis* |
| * Pricing varies with the reference substance needed and the number of repeats. | |
| HPTLC analyses | |
| 1 | HPTLC analysis |
| * Pricing varies with the reference substance needed and the number of repeats. | |
| Preparative HPLC analyses | |
| 1 | Sample dissolution / preparation |
| 2 | C18-column purification |
| 3 | Silica-column purification |
| 4 | Analytical method development |
| 5 | Sample drying (rotary evaporator) |
| 6 | Sample drying (desiccator) |
| * Prices are for a single-run analysis and include the mobile phase. | |
| * Prices apply when the user supplies the columns; columns supplied by us are charged in addition. | |
Biomaterials Laboratory
| No | Service |
|---|---|
| Spectrophotometer | |
| 1 | ATR – FTIR |
| Surface modification and analysis | |
| 1 | Goniometer / contact angle |
| 2 | O₂ plasma |
| Particle characterisation | |
| 1 | Particle size |
| 2 | Zeta potential |
| Mechanical testing | |
| 1 | Tensile test |
| 2 | Compression test |
| Mechanical test outputs | |
| 1 | Ultimate Tensile Strength (UTS) |
| 2 | Young's Modulus (E) |
| 3 | Compressive Stress (σ) |
| 4 | Compressive Modulus (E) |
| 5 | Elongation at Break (ɛ) |
Medical Device Testing Laboratory
| No | Service |
|---|---|
| Consultancy service | |
| 1 | Medical Device Regulation (MDR) |
| 2 | Product classification and rationale |
| 3 | List of international standards applicable to the device |
| 4 | Medical-device risk analysis report (to ISO 14971) |
| 5 | Medical-device usability report (to EN 62366) |
| 6 | Preparation of product technical specifications |
| 7 | Sterilisation methods and validation |
| 8 | Biocompatibility test reports (to ISO 10993) |
| 9 | Product verification and test reports to the product standard |
| 10 | Clinical evaluation and reporting |
| 11 | Medical-device validation |
| TESTS PERFORMED | |
| 1 | Oro-nasal CPAP/BPAP masks EN 17510:2020 |
| 2 | Nasal CPAP/BPAP masks EN 17510:2020 |
| 3 | Catheter mount BS 7143:1989 |
| 4 | Extendable patient circuit (breathing tubes) EN ISO 18562-2:2017 |
| 5 | Breathing exerciser (three-ball) |
| 6 | CPAP device EN ISO 80601-2-70:2020; EN ISO 17510-1:2009 |
| 7 | Nebuliser tubing and connector EN ISO 13544-2:2009 |
| 8 | Corrugated patient circuit (breathing tubes) EN ISO 18562-2:2017 |
| 9 | Nebuliser EN ISO 27427:2020 |
| 10 | LED phototherapy EN ISO 60601-2-50:2009 |
| 11 | TENS EN 60601-2-10:2015 |
| 12 | Nebuliser EN ISO 13544-1:2009 |
| 13 | Heating blanket TS EN 60601-2-35:2009 |
| 14 | Clean-room measurements EN ISO 14644-1 |
| 15 | Steam steriliser EN ISO 17665-1:2006; EN 285; EN 554 |
| 16 | Transport ventilator TS EN 794-3:1999 |
| 17 | Nebuliser ISO 18562 EN ISO 18562-1/2/3/4 |
Pharmaceutical Chemistry and Drug Metabolism Laboratory
| No | Service |
|---|---|
| 1 | In vitro drug metabolite determination |
| 2 | Mass-spectrum analysis of organic drugs |
| 3 | Synthesis of organic drugs and metabolites |
Pharmacology and Toxicology Laboratory
| No | Service |
|---|---|
| 1 | Cytotoxicity test (ISO 10993-5, biocompatibility testing of medical devices, cosmetics and drugs) |
| 2 | Cytotoxicity test (MTT assay, target-organ-specific cell line) |
| 3 | Cytotoxicity test (neutral red uptake assay, target-organ-specific cell line) |
| 4 | Cytotoxicity test (LDH assay, target-organ-specific cell line) |
| 5 | Ocular irritation test – EpiOcular™ (OECD TG 492)* |
| 6 | Skin irritation test – in vitro EpiDerm™ (OECD TG 439)* |
| 7 | Skin corrosion test – in vitro EpiDerm™ (OECD TG 431)* |
| * For irritation and corrosion tests, running more than the standard six samples at once is not recommended; larger sets need a separate schedule and budget. | |
Pharmaceutical Technology and Cosmetology Laboratory
| No | Service |
|---|---|
| 1 | Dynamic light scattering (DLS) – Zetasizer (particle size and size distribution, nano scale) |
| 2 | Dynamic light scattering (DLS) – Zetasizer (zeta potential) |
| 3 | Static light scattering (SLS) – Mastersizer (micron-scale particle size, wet or dry) |
| 4 | Elek testi 1 kg'a kadar |
| 5 | pH measurement (electrometric method) |
| 6 | Climatic test chamber (product stability and shelf-life determination) |
| 7 | Rheometer / viscometer (viscosity measurement) |
| 8 | Rheometer / viscometer (frequency sweep) |
| 9 | Rheometer / viscometer (strain sweep) |
| 10 | Rheometer / viscometer (temperature sweep, −40 °C to 200 °C) |
| 11 | Spray drying |
| 12 | Spectrophotometric measurements: per reading (UV-Vis) |
| 13 | Spectrophotometric measurements: with calibration, package (UV-Vis) |
| 14 | Sample preparation for spectrophotometric measurement (UV-Vis) |
| 15 | Microscopic imaging and photography (including fluorescent materials) |
| 16 | Powder / granule coating (fluidised bed) |
| 17 | Dissolution test – tablet |
| 18 | Dissolution test – capsule |
| 19 | Disintegration test – tablet |
| 20 | Disintegration test – capsule |
| 21 | Disintegration test – suppository |
| 22 | Hardness test (tablet) |
| 23 | Friability – tablet |
| 24 | Texture analysis CT3 (for the pharmaceutical, food-supplement and cosmetic industries: adhesiveness, elasticity, hardness, spreadability) |
| 25 | Tablet formulation and stability studies |
| 26 | Tablet stability studies |
| 27 | Capsule formulation and stability studies |
| 28 | Capsule stability studies |
| 29 | Liquid (solution, suspension, syrup) formulation and stability studies |
| 30 | Liquid (solution, suspension, syrup) stability studies |
| 31 | Cosmetic product formulation and stability studies |
| 32 | Cosmetic product stability studies |
| 33 | Cosmetic product challenge test |
| 34 | Hair combing |
| 35 | Hair breakage |
| 36 | Hair long-term use |
| 37 | Novel carrier-system formulations (liposomes, micro/nano carriers) |
| 38 | Topical product efficacy in vitro (Franz cell) tests |
Pharmacognosy and Phytotherapy Laboratory
| No | Service |
|---|---|
| 1 | HPTLC analysis* |
| 2 | GC-MS and GC-FID analysis* |
| 3 | Total phenolic content assay |
| 4 | Total flavonoid content assay |
| 5 | Total antioxidant activity assay (TOAC) |
| 6 | Ferric reducing antioxidant power assay (FRAP) |
| 7 | Cupric reducing antioxidant capacity assay (CUPRAC) |
| 8 | DPPH free-radical scavenging assay |
| 9 | DMPD free-radical scavenging assay |
| 10 | Elastase inhibition assay |
| 11 | Collagenase inhibition assay |
| 12 | Hyaluronidase inhibition assay |
| 13 | Tyrosinase inhibition assay |
| 14 | Urease inhibition assay |
| 15 | Acetylcholinesterase inhibition assay |
| 16 | Butyrylcholinesterase inhibition assay |
| 17 | Optical rotation test |
| 18 | Refractive index test |
| 19 | Relative density test |
| 20 | Acid value test |
| * Pricing varies with the reference substance needed and the number of repeats. | |
Pharmaceutical Microbiology Laboratory
| No | Service |
|---|---|
| 1 | EN ISO 11737 Microbiological evaluation of medical devices (sterility test, bioburden test) |
| 2 | BS ISO 22196 Measurement of antibacterial activity on plastics and other non-porous surfaces |
| 3 | BS ISO 4768 Measurement of anti-biofilm activity on plastics and other non-porous surfaces |
| 4 | TS EN ISO 22718 Cosmetics – Microbiology – Detection of Staphylococcus aureus |
| 5 | TS EN ISO 21150 Cosmetics – Microbiology – Detection of Escherichia coli |
| 6 | TS EN ISO 22717 Cosmetics – Microbiology – Detection of Pseudomonas aeruginosa |
| 7 | TS EN ISO 18416 Cosmetics – Microbiology – Detection of Candida albicans |
| 8 | TS EN ISO 21149 Cosmetics – Microbiology – Enumeration and detection of aerobic mesophilic bacteria |
| 9 | TS EN ISO 16212 Cosmetics – Microbiology – Enumeration of yeast and mould |
| 10 | TS EN ISO 11930 Cosmetics – Microbiology – Evaluation of the antimicrobial protection of a cosmetic product |
| 11 | Sterility test (European Pharmacopoeia 2.6.1) |
| 12 | Microbiological examination of non-sterile products (EP 2.6.12 / 2.6.13) |
| 13 | Bacterial endotoxin test (European Pharmacopoeia 2.6.14) |
| 14 | Bactericidal activity of disinfectants and antiseptics (TS EN 1276) |
| 15 | Fungicidal activity of disinfectants and antiseptics (TS EN 1650) |
| 16 | Antibacterial activity of plant or chemical substances (disk diffusion, minimum inhibitory concentration, minimum bactericidal concentration) |
| 17 | Antifungal activity of plant or chemical substances (disk diffusion, minimum inhibitory concentration, minimum fungicidal concentration) |
In Vivo Biocompatibility Laboratory
| No | Service |
|---|---|
| 1 | Systemic toxicity test ISO 10993-11 |
| 2 | Implantation test ISO 10993-6 |
| 3 | Pyrogenicity test ISO 10993-11 |
| 4 | Irritation test ISO 10993-23 |
Biochemistry Laboratory
| No | Service |
|---|---|
| 1 | Albumin (ALB), alanine aminotransferase (ALT), ammonia (NH3), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), glucose (GLU), creatinine (CREA), cholesterol (CHOL), total protein (TP), triglyceride (TRIG), urea (BUN), uric acid (URIC) |
| 2 | Alkaline phosphatase (ALKP), amylase (AMYL), inorganic phosphate (PHOS), calcium (Ca), creatine kinase (CK), lactate (LAC), lactate dehydrogenase (LDH), lipase 2 (LIPA), magnesium (MG), total bilirubin (TBIL) |
In Vivo Imaging Laboratory
| No | Service |
|---|---|
| 1 | 2D fluorescence / bioluminescence imaging |
| 2 | High-sensitivity 2D and 3D in vivo fluorescence and bioluminescence imaging |
| 3 | Cerenkov imaging |
| * +50 TL per additional animal in a single imaging session | |
Electron Microscopy Laboratory
| No | Service |
|---|---|
| SCANNING ELECTRON MICROSCOPY ANALYSES | |
| 1 | SEM sample sputter coating |
| 2 | SEM examination, high vacuum |
| 3 | SEM examination, low vacuum |
| 4 | SEM-EDS analysis |
| 5 | SEM tissue processing |
| 6 | SEM critical-point drying |
| 7 | Reporting service |
| TRANSMISSION ELECTRON MICROSCOPY ANALYSES | |
| 1 | TEM tissue processing, standard methods |
| 2 | Semi-thin sectioning on the ultramicrotome |
| 3 | Thin sectioning on the ultramicrotome |
| 4 | Contrast staining |
| 5 | Microscopic examination |
| 6 | Reporting service |
Biodesign Center
| No | Service |
|---|---|
| 1 | Design verification |
| 2 | Human-factors analysis |
| 3 | Risk analysis |
| 4 | UX/UI, system and product design analysis |
Biobank Unit
| No | Service |
|---|---|
| 1 | DNA isolation |
| 2 | RNA isolation |
| 3 | Serum isolation |
| 4 | Plasma isolation |
| 5 | Cell viability measurements |
| 6 | DNA/RNA purity and concentration analysis (NanoDrop) |
| 7 | DNA/RNA integrity analysis (Qubit) |
| 8 | Detailed DNA/RNA integrity analysis (Bioanalyzer) |
| 9 | White-cell isolation from blood |
| 10 | Protein concentration measurement (NanoDrop, Qubit) |
| 11 | Agarose gel electrophoresis |
| 12 | Snap-freezing of tissue in liquid nitrogen |
| 13 | Snap-freezing of tissue in isopentane (2-methylbutane) and liquid nitrogen |
| Biobanking service | |
| 1 | Request to store biological samples |
| 2 | Request to use biological samples |